Special features: Separate dog and cat commentary; storyboard comparisons; Teaching a new dog new tricks; HBO first look special.

Director of photography, Julio Macat ; editors, Michael A. Stevenson, Rick W. Finney ; music, John Debney ; production designer, James Bissell ; anamatronic effects supervisor, David Barclay ; visual effects supervisor, Ed Jones.

Jeff Goldblum, Elizabeth Perkins, Miriam Margolyes, Alexander Pollock; with the voice talents of Tobey Maguire, Alec Baldwin, Sean Hayes, Susan Sarandon, Joe Pantoliano, Michael Clarke Duncan, Jon Lovitz.

A look at the top-secret, high-tech espionage war going on between cats and dogs, which their humans are blissfully unaware of. The film follows Mr. Tinkle's (a cat) plan to destroy a new vaccine, that if developed, would eliminate all human allergies to dogs, and allow cats to rule the world. Lou, a beagle puppy accidentally becomes the dog-agent assigned to stop the cat plan.

Know to be man's best friends, cats and dogs have engaged in a fierce and merciless battle. Now, Mr. Tinkles, a ruthless cat, is plotting intensively to achieve nothing less than world domination. His main target is Professor Brody. The professor is working on a medication that will rid people of their dog hair allergies. Mr. Tinkles strives to get to the substance and have it analyzed. He then means to have it altered so that all humans of the world become allergic to any kind of dog. Cats would rule and dogs would then be exterminated. Lou is the Brody family's new puppy. He has never heard of dog agents and the major protective mission they fulfill towards the unsuspecting Brody family. Lou, along with Butch and a few other dog agents from the neighborhood desperately tries to hinder Mr. Tinkles in his sinister plans to take over the world.

MPAA rating: PG.

DVD.

Closed-captioned. Includes French dubbed version and subtitles in English, French or Spanish.